| Movie | Scream |
| Director(s) | Matt Bettinelli - OlpinTyler Gillett |
| Producer(s) | James Vanderbilt, William Sherak, Paul Neinstein |
| Writer(s) | James Vanderbilt, Guy Busick, Kevin Williamson |
| Running Time | 2:38:40 |
| Release Date | January 14, 2022 (USA) |
Watch Trailer:
Neve Adrianne Campbell playing as as Sidney Prescott
 | |
| Role | as Sidney Prescott |
| Real Name | Neve Adrianne Campbell |
| Age | 48 years old (in 2022) |
| Profession | Actress |
| Nationality | Canadian |
| Known for | Julia Salinger |
Courteney Bass Cox playing as as Gale Weathers
 | |
| Role | as Gale Weathers |
| Real Name | Courteney Bass Cox |
| Age | 57 years old (in 2022) |
| Profession | Actress, Producer, Director |
| Nationality | American |
| Known for | Bionic Woman |
David Arquette playing as as Dewey Riley
 | |
| Role | as Dewey Riley |
| Real Name | David Arquette |
| Age | 50 years old (in 2022) |
| Profession | Actor, film director, film producer, screenwriter, fashion designer |
| Nationality | American |
| Known for | Dark Angel 2016 |
Melissa Barrera Martinez playing as as Sam Carpenter
 | |
| Role | as Sam Carpenter |
| Real Name | Melissa Barrera Martinez |
| Age | 31 years old (in 2022) |
| Profession | Actress |
| Nationality | Mexican |
| Known for | Dos Veces T , Sacudete Las Penas, El Hotel, L for Leisure |
Jack Henry Quaid playing as as Richie Kirsch
 | |
| Role | as Richie Kirsch |
| Real Name | Jack Henry Quaid |
| Age | 29 years old (in 2022) |
| Profession | Actor |
| Nationality | American |
| Known for | Marvel |
Mikey Madison playing as as Amber Freeman
 | |
| Role | as Amber Freeman |
| Real Name | Mikey Madison |
| Age | 22 years old (in 2022) |
| Profession | Actress |
| Nationality | American |
| Known for | Max Fox |
Jenna Marie Ortega playing as as Tara Carpenter
 | |
| Role | as Tara Carpenter |
| Real Name | Jenna Marie Ortega |
| Profession | Actress |
| Nationality | American |
| Known for | The Flash (TV Show) |
Dylan Christopher Minnette playing as as Wes Hicks
 | |
| Role | as Wes Hicks |
| Real Name | Dylan Christopher Minnette |
| Age | 25 years old (in 2022) |
| Profession | American actor, Singer, Musician |
| Nationality | American |
| Known for | Gotham (2014), Jupiter's Legacy (2021) and Sneaky Pete (2015) |
Jasmin Savoy Brown playing as as Mindy Meeks-Martin
 | |
| Role | as Mindy Meeks-Martin |
| Real Name | Jasmin Savoy Brown |
| Age | 27 years old (in 2022) |
| Profession | Actress |
| Nationality | American |
| Known for | For The People (2018) |
Marley Eve Shelton playing as as Sheriff Judy Hicks
 | |
| Role | as Sheriff Judy Hicks |
| Real Name | Marley Eve Shelton |
| Age | 47 years old (in 2022) |
| Profession | Actress |
| Nationality | American |
| Known for | Grindhouse |
Bryan Ray Trout playing as as Billy Loomis
 | |
| Role | as Billy Loomis |
| Real Name | Bryan Ray Trout |
| Age | 52 years old (in 2022) |
| Profession | Actor |
| Nationality | American |
| Known for | Billy Loomis |
Kyle Steven Gallner playing as as Vince Schneider
 | |
| Role | as Vince Schneider |
| Real Name | Kyle Steven Gallner |
| Age | 35 years old (in 2022) |
| Profession | Actor |
| Nationality | American |
| Known for | Star Wars: The Last Jedi |
Chester Tam playing as as Deputy Vinson
 | |
| Role | as Deputy Vinson |
| Real Name | Chester Tam |
| Age | 40 years old (in 2022) |
| Profession | Actor |
| Nationality | Hong Kong |
| Known for | Take the 10 (2017) |
Heather Christina Marie Matarazzo playing as as Martha Meeks
 | |
| Role | as Martha Meeks |
| Real Name | Heather Christina Marie Matarazzo |
| Age | 39 years old (in 2022) |
| Profession | Actress |
| Nationality | American |
| Known for | Welcome to the Dollhouse, Roseanne, Now and Again, The Princess Diaries, The Princess Diaries 2: Royal Engagement, Scream 3 |
Drew Blythe Barrymore playing as Principal
 | |
| Role | Principal |
| Real Name | Drew Blythe Barrymore |
| Age | 47 years old (in 2022) |
| Profession | Actress |
| Nationality | American |
| Known for | Lahore Se Aagey |
Adam Jared Brody playing as Party Guest
 | |
| Role | Party Guest |
| Real Name | Adam Jared Brody |
| Age | 42 years old (in 2022) |
| Profession | Actor, Writer, Producer, Musician |
| Nationality | American |
| Known for | Pretty Guardian Sailor Moon |
Matthew Lyn Lillard playing as Flamethrower Ghostface
 | |
| Role | Flamethrower Ghostface |
| Real Name | Matthew Lyn Lillard |
| Age | 52 years old (in 2022) |
| Profession | Actor, Voice Actor, Director and Producer |
| Nationality | American |
| Known for | Scooby-Doo, SLC Punk, Without A Paddle, Summer Catch, The Groomsmen, Home Run Showdown, Return to Nim's Island |
Henry Franklin Winkler OBE playing as Party Guest
 | |
| Role | Party Guest |
| Real Name | Henry Franklin Winkler OBE |
| Age | 76 years old (in 2022) |
| Profession | Actor, Comedian, Director, Producer, Author |
| Nationality | American |
| Known for | Fonzie |